Youthinol® - a multi-ingredient longevity formula

As we age our body's natural production of DHEA declines dramatically. This decline leaves many researchers to believe DHEA may play an important role in the aging process and diseases related to aging. In patients between 50 and 79 years of age, DHEA levels are 40% lower in women and 35% lower in men who have cardiovascular disease than those without the disease. These results may be due to menopause or andropause (lowered testosterone production in men). No other sex hormone (including estrone, estradiol, testosterone or androstenedione) showed such decrease after age 50. DHEA, or dehydroepiandrosterone, is the most abundant hormone in humans and mammals. It is a building block for sexual and other hormones and determines general levels of well being and mood.

Research shows that DHEA may be the most critical single chemical in the body in predicting disease and health.

In a study at the University of California School of Medicine, La Jolla, DHEA was given to 13 men and 17 women aged 40 to 70 years. The subjects took either 50 mg. DHEA or a placebo every day for six months. Results showed that 84% of the women and 67% of the men taking DHEA showed a remarkable increase in perceived physical and psychological well-being as compared with the placebo group. The subjects taking DHEA reported an improved ability to deal with stressful situations, increased energy, deeper sleep, improved moods and more relaxed feelings.

Dr. William Regelson, MD, a worldwide leading expert on hormones in health and disease says DHEA is the "superstar of the super hormones" and that DHEA "actually makes you look, feel and think better." Dr. Arthur Schwartz from Temple University believes that DHEA shows promise as an anti-cancer agent and has found that DHEA protects laboratory animals from cancers of the breast, lung, colon, liver, skin, and lymphatic tissue. DHEA has been linked to a reduction in fear. It has been noted that DHEA operates as an anti-glucocorticoid. The negative physiological process of fear is dependent on activity in the hippocanipus, which is known to be dense in glucocorticoid receptors. DHEA replacement therapy has been shown to reduce the rate of breast cancer by 73% in a study where rats were given a mammary cancer-inducing substance called DMBA. The breast cancer rate in control animals remained at 95% compared with 27% for those with DHEA supplementation.

DHEA has been shown to enhance immune function significantly. In a study by SS Yen, with nine healthy men with an average age of 63 years old taking 50 mg. per day of DHEA orally over a 20-week period, post DHEA immune function was significantly enhanced. Levels of 13 different immune agents were increased by 20 to 62%.

DHEA supplements have been shown to increase energy levels, enhance memory and cognitive functions, reduce the ill effects of stress, improve immunity to diseases (including cancer), decrease body fat, enhance sex drive and possibly even extend life, and improve a mood. In several animal models, DHEA was shown to provide 100% protection against the potentially lethal effects of stress on the immune system. In recent human studies, DHEA has been shown to activate immune function significantly and DHEA has powerful immune-enhancing properties. DHEA has been called the "ultimate antioxidant" and it has been suggested that DHEA can block cancer during its early stages in animals. The body's production of DHEA drops from about 30 mg at age 20 to less than 6 mg per day at age 80. According to Dr. William Regelson of the Medical College of Virginia, DHEA is "one of the best biological bio-markers for chronological age. DHEA levels are directly related to mortality (the probability of dying) in humans. In a 12-year study of more than 240 men aged 50 to 79 years, researchers found that DHEA levels were inversely correlated with mortality, both from heart disease and from all causes. This finding suggests that DHEA-S (DHEA sulfate) level measurements can become a standard diagnostic predictor of disease, mortality and lifespan. Furthermore, if animal results hold true, supplemental DHEA may prevent disease, reduce mortality, and extend lifespan in humans. Dr. Eugene Roberts found that very low concentrations of DHEA were found to "increase the number of neurons, their ability to establish contacts, and their differentiation" in cell cultures. He also found that DHEA also enhanced long-term memory in mice undergoing avoidance training. It may play a similar role in human brain function.

DHEA and Alzheimer's Disease Evidence increasingly suggests that DHEA may be essential in maintaining the function of brain cells. Neurologists speculate that DHEA supplementation in humans may be an important ingredient both in slowing the progression of Alzheimer's and in treating the degenerative memory disorders that often arise in old age. The potential benefits of supplemental DHEA noted by researchers: Improved immune system, great ability to cope with stressful events, elevated moods, feeling of well-being, decreased fat, lift in energy, making bodies leaner, more relaxed feeling, improvement in concentration, promotes deeper and more restorative sleep, increases muscle strength and physical mobility.

Also, DHEA is being investigated for possible treatments of: osteoporosis, Epstein-barr viral infections, chronic fatigue syndrome, depression, menopause, herpes, aids, cancer, anti-obesity, diabetes, lupus.

Dosages for DHEA vary from 5 to 10 mg to as much as 2000 mg. Generally suggested dosages are 25 to 50 mg DHEA supplement taken in the morning before breakfast for men and 25 mg for women. It is generally suggested that the proper dosage would be that amount to bring blood DHEA and DHEA-S measurements toward young-adult (around 20 yr. old) level. These blood tests can be done by a physician.

Youthinol® contains OXO-7 analog. OXO-7 analog is the chemical equivalent of metabolized DHEA. In this metabolized state, OXO-7 can be potentially more effective than DHEA.

Most other DHEA products available on the market have a precursor. This means that these other products must still go through several extra steps before becoming DHEA. By the time the body makes the difficult conversion, much of the effectiveness of these precursors may be lost before they reach a form that is usable by the body. Neways has processed and refined the Discorea outside the body into an analogue, making it available for immediate use. This tends to eliminate undesirable side effects, which may result from using other forms of DHEA.

DHEA tends to support the regulation of healthy blood sugar levels, weight management programs, the normal functioning of cells, the immune system, and the maintenance of healthy bones.